Sanitary Risks Connected to the Consumption of Infusion from Senna rotundifolia L. Contaminated with Lead and Cadmium in Cotonou (Benin).

This study carried out an assessment of sanitary risks connected to the consumption of Senna rotundifolia Linn. contaminated with lead and cadmium. This plant was collected and analyzed by atomic absorption spectrophotometry. The results revealed a contamination of plants from markets of Dantokpa, Vossa, and Godomey with heavy metals. Senna from Vossa was higher in cadmium and lead levels (Pb: 2.733 mg/kg ± 0.356 mg/kg; Cd: 0.58 mg/kg ± 0.044 mg/kg) compared to the two other places (Pb: 1.825 mg/kg ± 0.133 mg/kg, Cd: 0.062 mg/kg ± 0.015 mg/kg and Pb: 1.902 mg/kg ± 0.265 mg/kg, Cd: 0.328 mg/kg ± 0.024 mg/kg), respectively, for Dantokpa and Godomey. In terms of risk assessment through the consumption of Senna, the values recorded for lead were nine times higher with children and six times higher with adults than the daily permissive intake (Pb: 3.376 × 10(-2) mg/kg/day for children and 2.105 × 10(-2) mg/kg/day for adults versus 3.6 × 10(-3) mg/kg/day for DPI). With respect to cadmium, there was no significant difference between the recorded values and the DPI (Cd: 1 × 14 10(-3) mg/ kg/day for children and Cd: 0.71 × 10(-3) mg/ kg/day for adults versus Cd: 1 × 10(-3) mg/kg/day for adults). This exposure of the population to lead and cadmium through the consumption of antimalarial healing plants could pose public health problems.

Magnesium content in seminal fluid as an indicator of chronic prostatitis.

Magnesium and zinc are both involved in a high number of enzymic activities vital for mammals. They are found in prostate in remarkably high concentrations and released into seminal fluid. Furthermore, drastic reduction of Zn and Mg concentrations in the semen fluid may lead to disorders in male fertility. We aimed to analyse the differences in Mg and Zn levels in the seminal plasma of 213 males including 48 normozoospermic, 30 azoospermic, 28 oligoasthenozoospermic, 22 asthenozoospermic and 85 chronic prostatitis. Mg and Zn concentrations were measured using an atomic absorption spectrophotometer. While zinc levels did not show correlation either with the volume of the sperm or the percentage of pathological forms, magnesium concentrations in seminal plasma were significantly decreased in chronic prostatitis patients as compared to other groups or normozoospermic patients (p<0.001). We propose therefore magnesium as a marker of prostatitis.